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Ambroxol hydrochloride
Product Name: Ambroxol hydrochloride
CAS No.: 23828-92-4
Molecular Formula:C13H19Br2ClN2O
Molecular Weight: 414.56
Description: Ambroxol hydrochloride, chemically known as 2-amino-3,5-dibromo-N-(trans-4-hydroxycyclohexyl)benzylamine, with the chemical formula C13H18Br2N2O-HCl, is an organic compound with a molecular weight of 414.56 and is a white to slightly yellow crystalline powder that is almost odorless. It promotes the elimination of mucous secretions from the interior of the respiratory tract and reduces the retention of mucus, thus significantly promoting sputum excretion. It is suitable for acute and chronic respiratory diseases with abnormal sputum secretion and poor expectorant function.
Application: It is an expectorant drug with good effect of dissolving mucous phlegm and lubricating the respiratory tract, promoting the secretion of lung surface active substances, secretion of respiratory fluid and cilia movement. It is used for the treatment of acute and chronic respiratory diseases and abnormal bronchial secretion.
Specification:

Item

Standard

Characters

Should be white or yellowish crystalline powder

IR absorpyion

Should be concordant with the RS spectrum

UV absorption

Should be concordant with the UV spectrum

TLC

The retention time of the main peak of the sample solution should be consistent with that of the control sample

Chlorides test

Should be positive reaction

Solubility

Should be soluble in methanol,insoluble in water and dichloromethane

Single impurity

¡Ü0.1%

Total impurities

¡Ü0.3%

Loss on drying

¡Ü0.5%

Melting point

235¡æ-240¡æ

PH value

4.5-6.0

Heavy metals

¡Ü20ppm

Sulfated ash

¡Ü0.1%

Assay

99.0%-101.0%

 
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